ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Hlx

Full Name:

H2.0-like homeobox

Alias:

Hlx1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H5|1 99.5 cM

Physical Location:

186551021-186556486 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3142 Symbol (Name): HLX (H2.0-like homeobox)

Ortholog Status:

The human GeneID 3142 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008250.1	NP_032276.1	NC_000067.5 range: 186551021..186556486, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND
GO:0005634	nucleus	Cellular Component	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	ISO
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0045627	positive regulation of T-helper 1 cell differentiation	Biological Process	IMP (16424184)
GO:0045629	negative regulation of T-helper 2 cell differentiation	Biological Process	IGI (16424184)
GO:0045629	negative regulation of T-helper 2 cell differentiation	Biological Process	IMP (16424184)
GO:0046622	positive regulation of organ growth	Biological Process	IMP (8557196)
GO:0048484	enteric nervous system development	Biological Process	IMP (16854219)
GO:0048513	organ development	Biological Process	IMP (8557196)
GO:0045627	positive regulation of T-helper 1 cell differentiation	Biological Process	IGI (16424184)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0001889	liver development	Biological Process	IMP (8557196)
GO:0030154	cell differentiation	Biological Process	IEA
GO:0008284	positive regulation of cell proliferation	Biological Process	IMP (8557196)
GO:0007519	skeletal muscle development	Biological Process	IMP (8557196)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0048558	embryonic gut morphogenesis	Biological Process	IMP (8557196)