ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Hmbs

Full Name:

hydroxymethylbilane synthase

Alias:

PBGD|T25658|Ups|Uros1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 A5.2|9 26.0 cM

Physical Location:

44144430-44152257 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3145 Symbol (Name): HMBS (hydroxymethylbilane synthase)

Ortholog Status:

The human GeneID 3145 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013551.2	NP_038579.2	NC_000075.5 range: 44144430..44152257, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0004418	hydroxymethylbilane synthase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006779	porphyrin biosynthetic process	Biological Process	IEA
GO:0006783	heme biosynthetic process	Biological Process	IEA
GO:0033014	tetrapyrrole biosynthetic process	Biological Process	IEA