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Gene Information
Gene ID:1543
Symbol:CYP1A1
Full Name:cytochrome P450, family 1, subfamily A, polypeptide 1
Alias:AHH|AHRR|CP11|CYP1|P1-450|P450-C|P450DX
Organism:Homo sapiens (Human)
Chromosome:15
Genetic Location:15q22-q24
Physical Location:72798942-72804929 on NC_000015.8, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 13076 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CYP1A1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
CYP1A11Alcohol-Induced Disorders
CYP1A12Alcoholism
CYP1A13Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000499.3NP_000490.1NC_000015.8 range: 72798942..72804929, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0005792microsomeCellular ComponentIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0020037heme bindingMolecular FunctionIEA
GO:0019825oxygen bindingMolecular FunctionTAS (1691986)
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenMolecular FunctionIEA
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0009055electron carrier activityMolecular FunctionIEA
GO:0050381unspecific monooxygenase activityMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:1543
HGNC:2595
Ensembl:ENSG00000140465
MIM:108330
HPRD:00148
HuGE Navigator:1543
dbSNP:CYP1A1
GeneCard:CYP1A1
AceView:CYP1A1