ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Lcp2

Full Name:

lymphocyte cytosolic protein 2

Alias:

Slp76

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

10q12

Physical Location:

19019977-19066743 on NC_005109.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3937 Symbol (Name): LCP2 (lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa))

Ortholog Status:

The human GeneID 3937 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		17517326
Method:		Microarray
Tissue:		Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:		The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_130421.2	NP_569105.1	NC_005109.2 range: 19019977..19066743

Gene Ontology (GO) Annotation