ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CYP7A1

Full Name:

cytochrome P450, family 7, subfamily A, polypeptide 1

Alias:

CP7A|CYP7|MGC126826|MGC138389

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

8q11-q12

Physical Location:

59565291-59575274 on NC_000008.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CYP7A1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000780.3	NP_000771.2	NC_000008.9 range: 59565291..59575274, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005789	endoplasmic reticulum membrane	Cellular Component	EXP (2384150)
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA
GO:0005792	microsome	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0008123	cholesterol 7-alpha-monooxygenase activity	Molecular Function	IEA
GO:0008123	cholesterol 7-alpha-monooxygenase activity	Molecular Function	EXP (2384150)
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0008202	steroid metabolic process	Biological Process	IEA
GO:0008203	cholesterol metabolic process	Biological Process	IEA
GO:0006699	bile acid biosynthetic process	Biological Process	NR
GO:0006629	lipid metabolic process	Biological Process	IEA