ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TTLL11

Full Name:

tubulin tyrosine ligase-like family, member 11

Alias:

C9orf20|bA244O19.1

Organism:

Homo sapiens (Human)

Chromosome:

9

Genetic Location:

9q33.2

Physical Location:

123791009-123895705 on NC_000009.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D9S934

2.28

0.0006

120135477

D9S1682

2.33

0.0005

124033322

Region:		120135477-124033322
Phenotype:		ONSET (age at onset of AD)
Name:		17067344
Method:		Linkage
Publication:		Kuo et al. Alcohol Clin Exp Res. (2006) Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence. PubMed
Summary:		A 4-cM dense whole-genome linkage study was conducted in the Irish Affected Sib Pair Study of Alcohol Dependence. Probands, affected siblings, and parents were evaluated by structured interview. Variance component linkage analysis was applied to data from 485 families for 5 measures: initial sensitivity and tolerance (based on scales from the self-report of the effects of ethanol; maximum drinks within 24 hours, an empirically derived factor score based on withdrawal symptoms, and age at onset of alcohol dependence.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_194252.2	NP_919228.2	NC_000009.10 range: 123791009..123895705, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005929	cilium	Cellular Component	IEA
GO:0004835	tubulin-tyrosine ligase activity	Molecular Function	IEA
GO:0016874	ligase activity	Molecular Function	IEA
GO:0006464	protein modification process	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000175764

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: