ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Igfbp4

Full Name:

insulin-like growth factor binding protein 4

Alias:

AI875747|Deb2|IGFBP-4

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 D

Physical Location:

98902573-98913959 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3487 Symbol (Name): IGFBP4 (insulin-like growth factor binding protein 4)

Ortholog Status:

The human GeneID 3487 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Igfbp4

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010517.3	NP_034647.1	NC_000077.5 range: 98902573..98913959

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (7510770\|7679139)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005520	insulin-like growth factor binding	Molecular Function	IPI (7679139)
GO:0019838	growth factor binding	Molecular Function	IEA
GO:0001558	regulation of cell growth	Biological Process	IEA