ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Il12b

Full Name:

interleukin 12b

Alias:

Il-12b|Il-12p40|Il12p40|p40

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 A5-B2|11 19.0 cM

Physical Location:

44213564-44227518 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3593 Symbol (Name): IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))

Ortholog Status:

The human GeneID 3593 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008352.2	NP_032378.1	NC_000077.5 range: 44213564..44227518

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043514	interleukin-12 complex	Cellular Component	IGI (7690439)
GO:0043514	interleukin-12 complex	Cellular Component	IDA (15220916)
GO:0016020	membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (7690439\|12855817\|12871593\|15220916\|15240714\|15692051)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0042164	interleukin-12 alpha subunit binding	Molecular Function	IPI (15220916)
GO:0042803	protein homodimerization activity	Molecular Function	IDA (12871593)
GO:0005125	cytokine activity	Molecular Function	IDA (11057672)
GO:0004896	hematopoietin/interferon-class (D200-domain) cytokine receptor activity	Molecular Function	IEA
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IDA (12871593)
GO:0042102	positive regulation of T cell proliferation	Biological Process	IDA (11057672)