ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Il2rb

Full Name:

interleukin 2 receptor, beta chain

Alias:

CD122|IL-15Rbeta|IL15Rbeta|Il-2/15Rbeta|Il-2Rbeta|MGC118674|p70

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E|15 43.3 cM

Physical Location:

78310977-78325451 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3560 Symbol (Name): IL2RB (interleukin 2 receptor, beta)

Ortholog Status:

The human GeneID 3560 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008368.3	NP_032394.1	NC_000081.5 range: 78310977..78325451, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0009897	external side of plasma membrane	Cellular Component	IDA (8262055\|16227984)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (16141072)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004896	hematopoietin/interferon-class (D200-domain) cytokine receptor activity	Molecular Function	IEA
GO:0004911	interleukin-2 receptor activity	Molecular Function	ISO
GO:0019976	interleukin-2 binding	Molecular Function	IPI (8262055)
GO:0019221	cytokine and chemokine mediated signaling pathway	Biological Process	ISO
GO:0045885	positive regulation of survival gene product expression	Biological Process	ISO