ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Irf1

Full Name:

interferon regulatory factor 1

Alias:

AU020929|Irf-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1.3|11 29.0 cM

Physical Location:

53583579-53590824 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3659 Symbol (Name): IRF1 (interferon regulatory factor 1)

Ortholog Status:

The human GeneID 3659 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008390.1	NP_032416.1	NC_000077.5 range: 53583579..53590824

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IC (14568984)
GO:0003677	DNA binding	Molecular Function	IDA (14568984)
GO:0003700	transcription factor activity	Molecular Function	IDA (14568984\|17159910)
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA (17159910)
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (14568984)
GO:0045084	positive regulation of interleukin-12 biosynthetic process	Biological Process	IMP (14568984)
GO:0045084	positive regulation of interleukin-12 biosynthetic process	Biological Process	IDA (14568984)
GO:0043374	CD8-positive, alpha-beta T cell differentiation	Biological Process	IMP (11359801)
GO:0010468	regulation of gene expression	Biological Process	IMP (11359801)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (17159910)