ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Irx3

Full Name:

Iroquois related homeobox 3 (Drosophila)

Alias:

AI894186

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 C5|8 42.1 cM

Physical Location:

94322423-94325272 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 79191 Symbol (Name): IRX3 (iroquois homeobox 3)

Ortholog Status:

The human GeneID 79191 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008393.2	NP_032419.2	NC_000074.5 range: 94322423..94325272, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (16100003)
GO:0003674	molecular_function	Molecular Function	ND
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0001822	kidney development	Biological Process	ISO
GO:0045665	negative regulation of neuron differentiation	Biological Process	IDA (10830170)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0045666	positive regulation of neuron differentiation	Biological Process	IDA (10830170)