ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Itga5

Full Name:

integrin alpha 5 (fibronectin receptor alpha)

Alias:

Cd49e|Fnra

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F3|15 57.4 cM

Physical Location:

103174716-103197193 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3678 Symbol (Name): ITGA5 (integrin, alpha 5 (fibronectin receptor, alpha polypeptide))

Ortholog Status:

The human GeneID 3678 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010577.2	NP_034707.2	NC_000081.5 range: 103174716..103197193, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0019717	synaptosome	Cellular Component	IDA (12904471)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0009897	external side of plasma membrane	Cellular Component	IDA (8557754)
GO:0008305	integrin complex	Cellular Component	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005178	integrin binding	Molecular Function	IPI (8601592)
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12867986\|12904471)
GO:0007613	memory	Biological Process	IMP (12904471)
GO:0007229	integrin-mediated signaling pathway	Biological Process	IEA
GO:0007159	leukocyte adhesion	Biological Process	IMP (8557754)
GO:0007157	heterophilic cell adhesion	Biological Process	IMP (8557754)
GO:0007155	cell adhesion	Biological Process	IEA
GO:0007044	cell-substrate junction assembly	Biological Process	IDA (12867986)
GO:0033631	cell-cell adhesion mediated by integrin	Biological Process	IMP (8557754)