Gene Information |
Gene ID: | | 16428 |
Symbol: | | Itk |
Full Name: | | IL2-inducible T-cell kinase |
Alias: | | Emt|Tcsk|Tsk |
Organism: | | Mus musculus (Mouse) |
Chromosome: | | 11 |
Genetic Location: | | 11 B1.1|11 22.0 cM |
Physical Location: | | 46138651-46203016 on NC_000077.5, complement |
Gene Type: | | protein-coding |
Human Ortholog: | | GeneID: 3702 Symbol (Name): ITK (IL2-inducible T-cell kinase) |
Ortholog Status: | | The human GeneID 3702 is not in current human dataset. |
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Gene in Ethanol Study Datasets |
QTL Information | QTL | Phenotype | Chr | Peak (cM) | LOD | P Value | Range | Status | QTL Link | |
Alcw3 | Acute Alcohol Withdrawal | 11 | 20 | 16-28 (cM) | 4.1 | 1.00E-05 | Significant | PARC | Caws4/Alcw3 | Chronic Alcohol Withdrawal | 11 | | 15-36 (cM) | 6.7 | 2.00E-07 | Significant | PARC |
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Gene Refseq Sequence Annotation |
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Gene Ontology (GO) Annotation |
GO ID | GO Term | Category | Evidence (PubMed) | |
GO:0016020 | membrane | Cellular Component | IEA | |
GO:0000166 | nucleotide binding | Molecular Function | IEA | |
GO:0016740 | transferase activity | Molecular Function | IEA | |
GO:0016301 | kinase activity | Molecular Function | IEA | |
GO:0008270 | zinc ion binding | Molecular Function | IEA | |
GO:0046872 | metal ion binding | Molecular Function | IEA | |
GO:0005524 | ATP binding | Molecular Function | IEA | |
GO:0005515 | protein binding | Molecular Function | IEA | |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | Molecular Function | IEA | |
GO:0004713 | protein-tyrosine kinase activity | Molecular Function | IEA | |
GO:0004672 | protein kinase activity | Molecular Function | IEA | |
GO:0007242 | intracellular signaling cascade | Biological Process | IEA | |
GO:0006468 | protein amino acid phosphorylation | Biological Process | IEA | |
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Other Database Cross Links |
NCBI Entrez Gene: | | 16428 |
MGI: | |
Ensembl: | | ENSMUSG00000020395 |
dbSNP: | | Itk |
AceView: | | Itk |