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Gene Information
Gene ID:16428
Symbol:Itk
Full Name:IL2-inducible T-cell kinase
Alias:Emt|Tcsk|Tsk
Organism:Mus musculus (Mouse)
Chromosome:11
Genetic Location:11 B1.1|11 22.0 cM
Physical Location:46138651-46203016 on NC_000077.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 3702    Symbol (Name): ITK (IL2-inducible T-cell kinase)
Ortholog Status:The human GeneID 3702 is not in current human dataset.
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw3Acute Alcohol Withdrawal112016-28 (cM)4.11.00E-05SignificantPARC
Caws4/Alcw3Chronic Alcohol Withdrawal11 15-36 (cM)6.72.00E-07SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_010583.2NP_034713.2NC_000077.5 range: 46138651..46203016, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0016301kinase activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0004715non-membrane spanning protein tyrosine kinase activityMolecular FunctionIEA
GO:0004713protein-tyrosine kinase activityMolecular FunctionIEA
GO:0004672protein kinase activityMolecular FunctionIEA
GO:0007242intracellular signaling cascadeBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:16428
MGI:
Ensembl:ENSMUSG00000020395
dbSNP:Itk
AceView:Itk