ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Jag1

Full Name:

jagged 1

Alias:

Headturner|Htu|Ozz|Ser-1|Serrate-1|slalom

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 F3|2 77.0 cM

Physical Location:

136907193-136942066 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 182 Symbol (Name): JAG1 (jagged 1 (Alagille syndrome))

Ortholog Status:

The human GeneID 182 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore2	Alcohol-induced Loss of Righting Reflex	2		75.6-81.7 (cM)	6.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013822.4	NP_038850.1	NC_000068.6 range: 136907193..136942066, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005886	plasma membrane	Cellular Component	IDA (16000382\|16495313)
GO:0016020	membrane	Cellular Component	IEA
GO:0005112	Notch binding	Molecular Function	IPI (10551863)
GO:0005509	calcium ion binding	Molecular Function	NAS (10551863)
GO:0005515	protein binding	Molecular Function	IPI (16000382)
GO:0042491	auditory receptor cell differentiation	Biological Process	IMP (16495313)
GO:0045596	negative regulation of cell differentiation	Biological Process	IMP (15064243)
GO:0045639	positive regulation of myeloid cell differentiation	Biological Process	IDA (15845452)
GO:0045747	positive regulation of Notch signaling pathway	Biological Process	IDA (15845452)
GO:0002011	morphogenesis of an epithelial sheet	Biological Process	IMP (11861489)
GO:0009887	organ morphogenesis	Biological Process	IMP (11181574)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007219	Notch signaling pathway	Biological Process	IEA
GO:0007154	cell communication	Biological Process	IEA
GO:0048839	inner ear development	Biological Process	IMP (16495313)