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Gene Information
Gene ID:1646
Symbol:AKR1C2
Full Name:aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
Alias:AKR1C-pseudo|BABP|DD|DD2|DDH2|HAKRD|HBAB|MCDR2
Organism:Homo sapiens (Human)
Chromosome:10
Genetic Location:10p15-p14
Physical Location:5021964-5050206 on NC_000010.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AKR1C2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001354.4NP_001345.1NC_000010.9 range: 5021964..5050206, complement
NM_205845.1NP_995317.1NC_000010.9 range: 5021964..5050206, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0032052bile acid bindingMolecular FunctionIDA (8573067)
GO:00470263-alpha-hydroxysteroid dehydrogenase (A-specific) activityMolecular FunctionIEA
GO:0047115trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activityMolecular FunctionIDA (8573067)
GO:0006629lipid metabolic processBiological ProcessIEA
GO:0006693prostaglandin metabolic processBiological ProcessIDA (8573067)
GO:0007586digestionBiological ProcessIDA (8573067)
GO:0008202steroid metabolic processBiological ProcessIDA (8573067)
Other Database Cross Links
NCBI Entrez Gene:1646
HGNC:385
Ensembl:ENSG00000151632
MIM:600450
HPRD:11857
HuGE Navigator:1646
dbSNP:AKR1C2
GeneCard:AKR1C2
AceView:AKR1C2