ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Kif5c

Full Name:

kinesin family member 5C

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 32.5 cM

Physical Location:

49474833-49630297 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3800 Symbol (Name): KIF5C (kinesin family member 5C)

Ortholog Status:

The human GeneID 3800 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		16783646
Method:		Microarray and QTL
Tissue:		Whole brain
Phenotype:		Alcohol preference, acute functional tolerance
Publication:		Saba et al. Mamm Genome. (2006) Candidate genes and their regulatory elements: alcohol preference and tolerance. PubMed
Summary:		Identified of 8 candidate genes for the trait of alcohol preference and 22 candidate genes for acute functional tolerance

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcp1	Alcohol Preference Drinking	2	28	19-35 (cM)	5.3		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008449.2	NP_032475.2	NC_000068.6 range: 49474833..49630297

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043005	neuron projection	Cellular Component	IDA (16301330)
GO:0035253	ciliary rootlet	Cellular Component	IDA (16018997)
GO:0005875	microtubule associated complex	Cellular Component	IEA
GO:0005874	microtubule	Cellular Component	IEA
GO:0005871	kinesin complex	Cellular Component	TAS (10964943)
GO:0005871	kinesin complex	Cellular Component	ISS (10964943)
GO:0005737	cytoplasm	Cellular Component	IDA (16018997)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10602484\|10964943)
GO:0003777	microtubule motor activity	Molecular Function	TAS (10964943)
GO:0003774	motor activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0007018	microtubule-based movement	Biological Process	IEA
GO:0008045	motor axon guidance	Biological Process	IMP (10964943)