ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Klf9

Full Name:

Kruppel-like factor 9

Alias:

AA589643|BTEB-1|Bteb1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C1

Physical Location:

23215715-23241400 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 687 Symbol (Name): KLF9 (Kruppel-like factor 9)

Ortholog Status:

The human GeneID 687 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Y14296
Fold Change:		1.7, 1.4, 1.6, 1.5
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010638.4	NP_034768.2	NC_000085.5 range: 23215715..23241400

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IDA (15117941)
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	ISS (15820306)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0030528	transcription regulator activity	Molecular Function	IDA (15117941)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0045449	regulation of transcription	Biological Process	IDA (15117941)
GO:0007566	embryo implantation	Biological Process	IDA (15117941)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0050847	progesterone receptor signaling pathway	Biological Process	IDA (15117941)