ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Klkb1

Full Name:

kallikrein B, plasma 1

Alias:

APS|Kal-3|Kal3|Klk3

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 B1-B3|8 26.0 cM

Physical Location:

46355024-46393819 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3818 Symbol (Name): KLKB1 (kallikrein B, plasma (Fletcher factor) 1)

Ortholog Status:

The human GeneID 3818 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008455.1	NP_032481.1	NC_000074.5 range: 46355024..46393819, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0003807	plasma kallikrein activity	Molecular Function	IEA
GO:0004252	serine-type endopeptidase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0006954	inflammatory response	Biological Process	IEA
GO:0007596	blood coagulation	Biological Process	IEA
GO:0042730	fibrinolysis	Biological Process	IEA