ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

DHCR7

Full Name:

7-dehydrocholesterol reductase

Alias:

SLOS

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11q13.2-q13.5

Physical Location:

70823104-70837124 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

DHCR7

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001360.2	NP_001351.2	NC_000011.8 range: 70823104..70837124, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005640	nuclear outer membrane	Cellular Component	IDA (9878250)
GO:0005783	endoplasmic reticulum	Cellular Component	IDA (9878250)
GO:0005789	endoplasmic reticulum membrane	Cellular Component	EXP (9465114)
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0047598	7-dehydrocholesterol reductase activity	Molecular Function	EXP (9465114)
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0047598	7-dehydrocholesterol reductase activity	Molecular Function	IDA (9465114)
GO:0006695	cholesterol biosynthetic process	Biological Process	IMP (9465114)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000172893

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: