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Gene Information
Gene ID:171900
Organism:Caenorhabditis elegans (Worm)
Physical Location:3264283-3266762 on NC_003279.5, complement
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Y44E3B.1
Note:Class II: late induction
Dataset Information
Phenotype:Ethanol response
Publication:Kwon et al. Genomics. (2004) Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. PubMed
Summary:We used in this report the nematode Caenorhabditis elegans as a model system to identify and characterize the genes that are affected by ethanol exposure and to link those genes functionally into an ethanol-induced gene network. By analyzing the expression profiles of all C. elegans ORFs using microarrays, we identified 230 genes affected by ethanol. While the ethanol response of some of the identified genes was significant at early time points, that of the majority was at late time points, indicating that the genes in the latter case might represent the physiological consequence of the ethanol exposure. We further characterized the early response genes that may represent those involved directly in the ethanol response. These genes included many heat shock protein genes, indicating that high concentration of ethanol acts as a strong stress to the animal.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001047238.2NP_001040703.1NC_003279.5 range: 3264283..3266762, complement
NM_058731.3NP_491132.1NC_003279.5 range: 3264283..3266762, complement
NM_058732.2NP_491133.1NC_003279.5 range: 3264283..3266762, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA (12520011|12654719)
GO:0003700transcription factor activityMolecular FunctionIEA (12520011|12654719)
GO:0043565sequence-specific DNA bindingMolecular FunctionIEA (12520011|12654719)
GO:0046983protein dimerization activityMolecular FunctionIEA (12520011|12654719)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA (12520011|12654719)
Other Database Cross Links
NCBI Entrez Gene:171900