ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mcm6

Full Name:

minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)

Alias:

ASP-l1|D1Wsu22e|Mcmd6

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 E4|1 66.6 cM

Physical Location:

130228167-130256232 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4175 Symbol (Name): MCM6 (minichromosome maintenance complex component 6)

Ortholog Status:

The human GeneID 4175 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008567.1	NP_032593.1	NC_000067.5 range: 130228167..130256232, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (11555636)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12192004)
GO:0003697	single-stranded DNA binding	Molecular Function	IPI (15917436)
GO:0003678	DNA helicase activity	Molecular Function	IPI (15917436)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0006260	DNA replication	Biological Process	IEA
GO:0006268	DNA unwinding during replication	Biological Process	IPI (15917436)
GO:0006270	DNA replication initiation	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0007049	cell cycle	Biological Process	IEA