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Gene Information
Gene ID:1728
Full Name:NAD(P)H dehydrogenase, quinone 1
Organism:Homo sapiens (Human)
Genetic Location:16q22.1
Physical Location:68300804-68318033 on NC_000016.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:NQO1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
NQO11Alcohol-Induced Disorders
NQO11Alcohol-Induced Disorders Nervous System
NQO11Alcohol-Related Disorders
NQO11Alcohol Withdrawal Delirium
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000903.2NP_000894.1NC_000016.8 range: 68300804..68318033, complement
NM_001025433.1NP_001020604.1NC_000016.8 range: 68300804..68318033, complement
NM_001025434.1NP_001020605.1NC_000016.8 range: 68300804..68318033, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentTAS (2843525)
GO:0003955NAD(P)H dehydrogenase (quinone) activityMolecular FunctionTAS (10393963)
GO:0004128cytochrome-b5 reductase activityMolecular FunctionTAS (9579781)
GO:0009055electron carrier activityMolecular FunctionIEA
GO:0050662coenzyme bindingMolecular FunctionIEA
GO:0006805xenobiotic metabolic processBiological ProcessTAS (10393963)
GO:0006809nitric oxide biosynthetic processBiological ProcessTAS (9579781)
GO:0007271synaptic transmission, cholinergicBiological ProcessTAS (9579781)
GO:0009636response to toxinBiological ProcessTAS (10393963)
Other Database Cross Links
NCBI Entrez Gene:1728
HuGE Navigator:1728