ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

F09E5.8

Organism:

Caenorhabditis elegans (Worm)

Chromosome:

Physical Location:

5350639-5351921 on NC_003280.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 11212 Symbol (Name): PROSC (proline synthetase co-transcribed homolog (bacterial))

Ortholog Status:

The human GeneID 11212 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		F09E5.8
Note:		Class II: late induction

Dataset Information

Name:		15028283
Method:		Microarray
Phenotype:		Ethanol response
Publication:		Kwon et al. Genomics. (2004) Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. PubMed
Summary:		We used in this report the nematode Caenorhabditis elegans as a model system to identify and characterize the genes that are affected by ethanol exposure and to link those genes functionally into an ethanol-induced gene network. By analyzing the expression profiles of all C. elegans ORFs using microarrays, we identified 230 genes affected by ethanol. While the ethanol response of some of the identified genes was significant at early time points, that of the majority was at late time points, indicating that the genes in the latter case might represent the physiological consequence of the ethanol exposure. We further characterized the early response genes that may represent those involved directly in the ethanol response. These genes included many heat shock protein genes, indicating that high concentration of ethanol acts as a strong stress to the animal.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_062600.3	NP_495001.1	NC_003280.6 range: 5350639..5351921

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0009792	embryonic development ending in birth or egg hatching	Biological Process	IMP (14551910)