| Gene Information |
| Gene ID: | | 176569 |
| Symbol: | | dpy-18 |
| Organism: | | Caenorhabditis elegans (Worm) |
| Chromosome: | | III |
| Physical Location: | | 11372762-11378334 on NC_003281.7, complement |
| Gene Type: | | protein-coding |
| Human Ortholog: | | This gene has no human ortholog. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | Y47D3B.10 | | Note: | | Class II: late induction |
| | Dataset Information | | Name: | | 15028283 | | Method: | | Microarray | | Phenotype: | | Ethanol response | | Publication: | | Kwon et al. Genomics. (2004) Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. PubMed | | Summary: | | We used in this report the nematode Caenorhabditis elegans as a model system to identify and characterize the genes that are affected by ethanol exposure and to link those genes functionally into an ethanol-induced gene network. By analyzing the expression profiles of all C. elegans ORFs using microarrays, we identified 230 genes affected by ethanol. While the ethanol response of some of the identified genes was significant at early time points, that of the majority was at late time points, indicating that the genes in the latter case might represent the physiological consequence of the ethanol exposure. We further characterized the early response genes that may represent those involved directly in the ethanol response. These genes included many heat shock protein genes, indicating that high concentration of ethanol acts as a strong stress to the animal. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005488 | binding | Molecular Function | IEA (12520011|12654719) | |
| GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | Molecular Function | IEA (12520011|12654719) | |
| GO:0009790 | embryonic development | Biological Process | IMP (10805750) | |
| GO:0010171 | body morphogenesis | Biological Process | IMP (4366476|14551910) | |
| GO:0019538 | protein metabolic process | Biological Process | IEA (12520011|12654719) | |
| GO:0040002 | collagen and cuticulin-based cuticle development | Biological Process | IMP (10805750) | |
| GO:0040011 | locomotion | Biological Process | IMP (12529635) | |
| GO:0040018 | positive regulation of multicellular organism growth | Biological Process | IGI (17374156) | |
| GO:0040018 | positive regulation of multicellular organism growth | Biological Process | IMP (12529635) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 176569 |
| WormBase: | | WBGene00001077 |
