ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nfe2

Full Name:

nuclear factor, erythroid derived 2

Alias:

45kDa|NF-E2|p45|p45NFE2|p45nf-e2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F3|15 61.7 cM

Physical Location:

103078647-103085846 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4778 Symbol (Name): NFE2 (nuclear factor (erythroid-derived 2), 45kDa)

Ortholog Status:

The human GeneID 4778 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008685.2	NP_032711.2	NC_000081.5 range: 103078647..103085846, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0046983	protein dimerization activity	Molecular Function	IEA
GO:0003713	transcription coactivator activity	Molecular Function	RCA (12466851)
GO:0003700	transcription factor activity	Molecular Function	RCA (12466851)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	RCA (12466851)
GO:0007275	multicellular organismal development	Biological Process	RCA (12466851)
GO:0007599	hemostasis	Biological Process	RCA (12466851)
GO:0008015	blood circulation	Biological Process	RCA (12466851)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	RCA (12466851)