ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nfe2l2

Full Name:

nuclear factor, erythroid derived 2, like 2

Alias:

AI194320|Nrf2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 C3|2 45.0 cM

Physical Location:

75513575-75542697 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4780 Symbol (Name): NFE2L2 (nuclear factor (erythroid-derived 2)-like 2)

Ortholog Status:

The human GeneID 4780 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010902.3	NP_035032.1	NC_000068.6 range: 75513575..75542697, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (14517290\|15087497\|15870285)
GO:0005737	cytoplasm	Cellular Component	IPI (14517290)
GO:0003677	DNA binding	Molecular Function	IDA (12220541\|14517290\|15870285)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0030528	transcription regulator activity	Molecular Function	IGI (15087497)
GO:0016563	transcription activator activity	Molecular Function	IDA (15870285)
GO:0046983	protein dimerization activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (14517290\|15870285)
GO:0003700	transcription factor activity	Molecular Function	IDA (12220541\|14517290)
GO:0045995	regulation of embryonic development	Biological Process	IGI (15087497)
GO:0045941	positive regulation of transcription	Biological Process	IDA (15870285)
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (14517290)
GO:0045449	regulation of transcription	Biological Process	IGI (15087497)
GO:0030968	unfolded protein response	Biological Process	IDA (14517290)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (12220541)