ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nfkb2

Full Name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100

Alias:

NF-kappaB2|lyt|p49|p49/p100|p50B|p52

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3-D2|19 45.75 cM

Physical Location:

46380107-46386579 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4791 Symbol (Name): NFKB2 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100))

Ortholog Status:

The human GeneID 4791 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_019408.2	NP_062281.1	NC_000085.5 range: 46380107..46386579

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (10402669)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0002268	follicular dendritic cell differentiation	Biological Process	IMP (10586052)
GO:0048535	lymph node development	Biological Process	TAS (10687308)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0030198	extracellular matrix organization and biogenesis	Biological Process	IMP (10586052)
GO:0007165	signal transduction	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0002467	germinal center formation	Biological Process	IMP (10586052)
GO:0048536	spleen development	Biological Process	IMP (10586052)