ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

18089

Symbol:

Nkx2-3

Full Name:

NK2 transcription factor related, locus 3 (Drosophila)

Alias:

Nkx-2.3|Nkx2.3|tinman

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3|19 42.0 cM

Physical Location:

43686814-43690381 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 159296 Symbol (Name): NKX2-3 (NK2 transcription factor related, locus 3 (Drosophila))

Ortholog Status:

The human GeneID 159296 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008699.2	NP_032725.1	NC_000085.5 range: 43686814..43690381

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0001776	leukocyte homeostasis	Biological Process	IMP (10926756)
GO:0043367	CD4-positive, alpha beta T cell differentiation	Biological Process	IMP (10926756)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (10926756)
GO:0048535	lymph node development	Biological Process	IMP (10926756)
GO:0048536	spleen development	Biological Process	IMP (10926756)
GO:0048537	mucosal-associated lymphoid tissue development	Biological Process	IMP (10926756)
GO:0048565	gut development	Biological Process	IMP (10926756)
GO:0048621	post-embryonic gut morphogenesis	Biological Process	IMP (10926756)
GO:0030225	macrophage differentiation	Biological Process	IMP (10926756)
GO:0030183	B cell differentiation	Biological Process	IMP (12682228)
GO:0002317	plasma cell differentiation	Biological Process	IMP (10926756)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006641	triacylglycerol metabolic process	Biological Process	IMP (10926756)
GO:0006955	immune response	Biological Process	IMP (12682228)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0009791	post-embryonic development	Biological Process	IMP (10926756)
GO:0016333	morphogenesis of follicular epithelium	Biological Process	IMP (10926756)
GO:0022612	gland morphogenesis	Biological Process	IMP (10926756)
GO:0050900	leukocyte migration	Biological Process	IMP (10926756)