ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nkx2-6

Full Name:

NK2 transcription factor related, locus 6 (Drosophila)

Alias:

AV044928|Nkx-2.6|Nkx2.6|Tix|tinman

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D2|14 30.0 cM

Physical Location:

69790075-69793596 on NC_000080.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 137814 Symbol (Name): NKX2-6 (NK2 transcription factor related, locus 6 (Drosophila))

Ortholog Status:

The human GeneID 137814 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010920.1	NP_035050.1	NC_000080.5 range: 69790075..69793596

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND
GO:0005634	nucleus	Cellular Component	IEA
GO:0003674	molecular_function	Molecular Function	ND
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0043066	negative regulation of apoptosis	Biological Process	IGI (11390666)
GO:0030154	cell differentiation	Biological Process	IGI (11390666)
GO:0008284	positive regulation of cell proliferation	Biological Process	IGI (11390666)
GO:0007507	heart development	Biological Process	IGI (11390666)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0060037	pharyngeal system development	Biological Process	IGI (11390666)