ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nkx3-1

Full Name:

NK-3 transcription factor, locus 1 (Drosophila)

Alias:

Bax|NKX3.1|NKX3A|Nkx-3.1|bagpipe

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D2|14 30.0 cM

Physical Location:

69808748-69812714 on NC_000080.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4824 Symbol (Name): NKX3-1 (NK3 homeobox 1)

Ortholog Status:

The human GeneID 4824 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010921.3	NP_035051.1	NC_000080.5 range: 69808748..69812714

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15987773)
GO:0003677	DNA binding	Molecular Function	IDA (10993896)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0016563	transcription activator activity	Molecular Function	IDA (10993896)
GO:0008134	transcription factor binding	Molecular Function	IDA (10993896)
GO:0003700	transcription factor activity	Molecular Function	IDA (10993896)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007431	salivary gland development	Biological Process	IMP (10906459)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (10993896)
GO:0006350	transcription	Biological Process	IEA
GO:0030850	prostate gland development	Biological Process	IMP (10215624\|10906459\|11002344)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0048754	branching morphogenesis of a tube	Biological Process	IMP (11002344)
GO:0050680	negative regulation of epithelial cell proliferation	Biological Process	IMP (11002344)