ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Slc11a2

Full Name:

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Alias:

DCT1|DMT1|Nramp2|mk|van

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F1|15 59.8 cM

Physical Location:

100218328-100253413 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4891 Symbol (Name): SLC11A2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2)

Ortholog Status:

The human GeneID 4891 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008732.1	NP_032758.1	NC_000081.5 range: 100218328..100253413, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0005768	endosome	Cellular Component	IDA (16227996)
GO:0005769	early endosome	Cellular Component	IDA (12724326)
GO:0005886	plasma membrane	Cellular Component	IDA (12724326\|16227996)
GO:0012505	endomembrane system	Cellular Component	IDA (12724326)
GO:0015087	cobalt ion transmembrane transporter activity	Molecular Function	IDA (12724326\|16142913)
GO:0005215	transporter activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0005381	iron ion transmembrane transporter activity	Molecular Function	IDA (16142913)
GO:0006824	cobalt ion transport	Biological Process	IDA (12724326\|16142913)
GO:0006826	iron ion transport	Biological Process	IDA (16142913)
GO:0006826	iron ion transport	Biological Process	IMP (15994289)
GO:0006810	transport	Biological Process	IEA
GO:0006811	ion transport	Biological Process	IEA