ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

P4ha2

Full Name:

procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide

Alias:

AA407196|C76437|P4hl

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 29.2 cM

Physical Location:

53915017-53945149 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8974 Symbol (Name): P4HA2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II)

Ortholog Status:

The human GeneID 8974 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011031.1	NP_035161.1	NC_000077.5 range: 53915017..53945149

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0004656	procollagen-proline 4-dioxygenase activity	Molecular Function	IDA (7753822)
GO:0031418	L-ascorbic acid binding	Molecular Function	IEA
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	Molecular Function	IEA
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (7753822)
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Biological Process	IDA (7753822)
GO:0019538	protein metabolic process	Biological Process	IEA