ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

18508

Symbol:

Pax6

Full Name:

paired box gene 6

Alias:

1500038E17Rik|AEY11|Dey|Gsfaey11|Pax-6|Sey

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E3|2 58.0 cM

Physical Location:

105516601-105537225 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5080 Symbol (Name): PAX6 (paired box 6)

Ortholog Status:

The human GeneID 5080 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013627.4	NP_038655.1	NC_000068.6 range: 105516601..105537225

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (11209945\|12050133\|14625556\|16464444)
GO:0005667	transcription factor complex	Cellular Component	TAS (10197584)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (12756174)
GO:0003700	transcription factor activity	Molecular Function	TAS (10197584)
GO:0005515	protein binding	Molecular Function	IPI (16098226)
GO:0042462	eye photoreceptor cell development	Biological Process	IMP (12648492)
GO:0033365	protein localization in organelle	Biological Process	IMP (16024294)
GO:0030900	forebrain development	Biological Process	IMP (15514979\|15548580\|15758185)
GO:0030858	positive regulation of epithelial cell differentiation	Biological Process	IMP (16080917)
GO:0030334	regulation of cell migration	Biological Process	IMP (10409504)
GO:0030216	keratinocyte differentiation	Biological Process	IMP (16080917)
GO:0030154	cell differentiation	Biological Process	IMP (15031110)
GO:0043010	camera-type eye development	Biological Process	IGI (12072567\|12183364)
GO:0043010	camera-type eye development	Biological Process	IMP (11062307\|11069887\|12648492\|12756174\|16080917)
GO:0045165	cell fate commitment	Biological Process	IGI (15229646)
GO:0045165	cell fate commitment	Biological Process	IMP (15878992)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0045665	negative regulation of neuron differentiation	Biological Process	IGI (16950124)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (15905411)
GO:0050680	negative regulation of epithelial cell proliferation	Biological Process	IMP (16080917)
GO:0050767	regulation of neurogenesis	Biological Process	IMP (15548580)
GO:0021983	pituitary gland development	Biological Process	IMP (10588713)
GO:0021905	forebrain-midbrain boundary formation	Biological Process	IMP (9169845)
GO:0021902	commitment of a neuronal cell to a specific type of neuron in the forebrain	Biological Process	IMP (11124115)
GO:0001709	cell fate determination	Biological Process	IMP (12756174)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	TAS (10197584)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007409	axonogenesis	Biological Process	IMP (15514979)
GO:0007411	axon guidance	Biological Process	IMP (11967891\|14586016)
GO:0007420	brain development	Biological Process	IMP (10409504\|12196586)
GO:0007435	salivary gland morphogenesis	Biological Process	IMP (11731698)
GO:0008285	negative regulation of cell proliferation	Biological Process	IMP (15548580)
GO:0009950	dorsal/ventral axis specification	Biological Process	IMP (10588713)
GO:0009952	anterior/posterior pattern formation	Biological Process	IGI (15917450)
GO:0009952	anterior/posterior pattern formation	Biological Process	IMP (12196586)
GO:0009953	dorsal/ventral pattern formation	Biological Process	IMP (15548580\|15878992)
GO:0021543	pallium development	Biological Process	IMP (11124115)
GO:0021797	forebrain anterior/posterior pattern formation	Biological Process	IMP (9169845)
GO:0021798	forebrain dorsal/ventral pattern formation	Biological Process	IMP (11050125\|11124115)
GO:0001764	neuron migration	Biological Process	IMP (15758185)