ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Pla2g2a

Full Name:

phospholipase A2, group IIA (platelets, synovial fluid)

Alias:

EF|Mom1|Pla2|sPLA2|sPla2-IIA

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D3|4 68.0 cM

Physical Location:

138387771-138391103 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5320 Symbol (Name): PLA2G2A (phospholipase A2, group IIA (platelets, synovial fluid))

Ortholog Status:

The human GeneID 5320 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NR_002926.3	-	NC_000070.5 range: 138387771..138391103

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0004623	phospholipase A2 activity	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0050678	regulation of epithelial cell proliferation	Biological Process	IGI (8978062\|8978063\|9159163)
GO:0035019	somatic stem cell maintenance	Biological Process	IGI (1541640)
GO:0016042	lipid catabolic process	Biological Process	IEA
GO:0001558	regulation of cell growth	Biological Process	IEA
GO:0006644	phospholipid metabolic process	Biological Process	IEA
GO:0050680	negative regulation of epithelial cell proliferation	Biological Process	IGI (9288104)