ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Plcb4

Full Name:

phospholipase C, beta 4

Alias:

A930039J07Rik|AI854601|C230058B11Rik

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 F3|2 77.0 cM

Physical Location:

135567565-135838803 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5332 Symbol (Name): PLCB4 (phospholipase C, beta 4)

Ortholog Status:

The human GeneID 5332 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore2	Alcohol-induced Loss of Righting Reflex	2		75.6-81.7 (cM)	6.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013829.2	NP_038857.1	NC_000068.6 range: 135567565..135838803

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0030425	dendrite	Cellular Component	IDA (15579147)
GO:0014069	postsynaptic density	Cellular Component	IDA (15579147)
GO:0005792	microsome	Cellular Component	IDA (15579147)
GO:0005790	smooth endoplasmic reticulum	Cellular Component	IDA (15579147)
GO:0005634	nucleus	Cellular Component	IDA (15579147)
GO:0005515	protein binding	Molecular Function	IPI (15579147)
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0004629	phospholipase C activity	Molecular Function	RCA (16141072)
GO:0004435	phosphoinositide phospholipase C activity	Molecular Function	RCA (16141072)
GO:0006629	lipid metabolic process	Biological Process	RCA (16141072)
GO:0007165	signal transduction	Biological Process	RCA (16141072)
GO:0007242	intracellular signaling cascade	Biological Process	RCA (16141072)