ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Plcd4

Full Name:

phospholipase C, delta 4

Alias:

4921507K24Rik

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C3|1 39.2 cM

Physical Location:

74589462-74612550 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 84812 Symbol (Name): PLCD4 (phospholipase C, delta 4)

Ortholog Status:

The human GeneID 84812 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC
Lore1	Alcohol-induced Loss of Righting Reflex	1		36.9-41 (cM)	5.4		Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005622	intracellular	Cellular Component	IDA (2033248)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0004435	phosphoinositide phospholipase C activity	Molecular Function	RCA (12466851)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	RCA (12466851)
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0004629	phospholipase C activity	Molecular Function	TAS (2033248)
GO:0007165	signal transduction	Biological Process	TAS (11340203)
GO:0007242	intracellular signaling cascade	Biological Process	RCA (12466851)
GO:0007340	acrosome reaction	Biological Process	IMP (11340203)
GO:0016042	lipid catabolic process	Biological Process	IEA
GO:0030384	phosphoinositide metabolic process	Biological Process	TAS (11340203)
GO:0006629	lipid metabolic process	Biological Process	RCA (12466851)