ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Pld2

Full Name:

phospholipase D2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B3|11 39.0 cM

Physical Location:

70353665-70371611 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5338 Symbol (Name): PLD2 (phospholipase D2)

Ortholog Status:

The human GeneID 5338 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008876.2	NP_032902.1	NC_000077.5 range: 70353665..70371611

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	IDA (14718562)
GO:0031526	brush border membrane	Cellular Component	IDA (15598876)
GO:0016020	membrane	Cellular Component	IEA
GO:0035091	phosphoinositide binding	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0004630	phospholipase D activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016042	lipid catabolic process	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA
GO:0007154	cell communication	Biological Process	IEA
GO:0006898	receptor-mediated endocytosis	Biological Process	IDA (14718562)
GO:0002031	G-protein coupled receptor internalization	Biological Process	IDA (14718562)