ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Prrx1

Full Name:

paired related homeobox 1

Alias:

A230024N07Rik|AA755424|AI385634|AI843499|K-2|Pmx1|Prx1|mHox

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H2.1|1 85.4 cM

Physical Location:

165175249-165243780 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5396 Symbol (Name): PRRX1 (paired related homeobox 1)

Ortholog Status:

The human GeneID 5396 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (11748565)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (15459107)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0045880	positive regulation of smoothened signaling pathway	Biological Process	IGI (11532916)
GO:0048701	embryonic cranial skeleton morphogenesis	Biological Process	IGI (9729491)
GO:0048704	embryonic skeletal morphogenesis	Biological Process	IGI (9729491\|9876178\|11532916)
GO:0048844	artery morphogenesis	Biological Process	IGI (10664157)
GO:0048844	artery morphogenesis	Biological Process	IMP (10664157)
GO:0002053	positive regulation of mesenchymal cell proliferation	Biological Process	IGI (11532916)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0042474	middle ear morphogenesis	Biological Process	IGI (9729491)
GO:0042472	inner ear morphogenesis	Biological Process	IGI (9729491)
GO:0030326	embryonic limb morphogenesis	Biological Process	IGI (9729491\|9882503)
GO:0007275	multicellular organismal development	Biological Process	RCA (12466851)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0051216	cartilage development	Biological Process	IGI (9876178)