ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ABCA1

Full Name:

ATP-binding cassette, sub-family A (ABC1), member 1

Alias:

ABC-1|ABC1|CERP|FLJ14958|HDLDT1|MGC164864|MGC165011|TGD

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

9q31.1

Physical Location:

106583103-106730256 on NC_000009.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ABCA1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005502.2	NP_005493.2	NC_000009.10 range: 106583103..106730256, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	IDA (10525055)
GO:0045335	phagocytic vesicle	Cellular Component	IDA (15469992)
GO:0045121	membrane raft	Cellular Component	IDA (15469992)
GO:0016020	membrane	Cellular Component	IEA
GO:0005624	membrane fraction	Cellular Component	IDA (10525055)
GO:0016887	ATPase activity	Molecular Function	IEA
GO:0017127	cholesterol transporter activity	Molecular Function	IDA (12084722)
GO:0030226	apolipoprotein receptor activity	Molecular Function	IDA (16443932)
GO:0030226	apolipoprotein receptor activity	Molecular Function	IPI (11162594)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0030349	syntaxin-13 binding	Molecular Function	IPI (15469992)
GO:0031267	small GTPase binding	Molecular Function	IPI (16443932)
GO:0015485	cholesterol binding	Molecular Function	IC (12084722)
GO:0005543	phospholipid binding	Molecular Function	IC (16702602)
GO:0005515	protein binding	Molecular Function	IPI (16192269)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005548	phospholipid transporter activity	Molecular Function	IDA (16702602)
GO:0008203	cholesterol metabolic process	Biological Process	IEA
GO:0033700	phospholipid efflux	Biological Process	IDA (10431236\|11162594)
GO:0033700	phospholipid efflux	Biological Process	IMP (16702602)
GO:0042632	cholesterol homeostasis	Biological Process	IDA (10431236)
GO:0043691	reverse cholesterol transport	Biological Process	IMP (10431236)
GO:0050702	interleukin-1 beta secretion	Biological Process	IMP (11855831)
GO:0055091	phospholipid homeostasis	Biological Process	IMP (16702602)
GO:0033344	cholesterol efflux	Biological Process	IMP (16443932)
GO:0033344	cholesterol efflux	Biological Process	IDA (10431236\|11162594)
GO:0032488	Cdc42 protein signal transduction	Biological Process	IMP (16443932)
GO:0008202	steroid metabolic process	Biological Process	IEA
GO:0016197	endosome transport	Biological Process	IDA (14747463)
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IMP (16443932)
GO:0007040	lysosome organization and biogenesis	Biological Process	IDA (15163665)
GO:0006810	transport	Biological Process	IEA
GO:0006629	lipid metabolic process	Biological Process	IEA
GO:0030819	positive regulation of cAMP biosynthetic process	Biological Process	IMP (14701824)
GO:0032367	intracellular cholesterol transport	Biological Process	IMP (10431236)
GO:0060155	platelet dense granule organization and biogenesis	Biological Process	IMP (15163665)