ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

EDN1

Full Name:

endothelin 1

Alias:

ET1|HDLCQ7

Organism:

Homo sapiens (Human)

Chromosome:

6

Genetic Location:

6p24.1

Physical Location:

12398514-12405412 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

EDN1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001955.3	NP_001946.3	NC_000006.10 range: 12398514..12405412

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (10770212\|16820593)
GO:0005737	cytoplasm	Cellular Component	IDA (12379507)
GO:0005179	hormone activity	Molecular Function	IDA (10770212)
GO:0031708	endothelin B receptor binding	Molecular Function	IDA (10770212)
GO:0031707	endothelin A receptor binding	Molecular Function	IDA (10770212)
GO:0046887	positive regulation of hormone secretion	Biological Process	IDA (10770212)
GO:0045321	leukocyte activation	Biological Process	TAS (16820593)
GO:0043406	positive regulation of MAP kinase activity	Biological Process	IDA (10770212)
GO:0042313	protein kinase C deactivation	Biological Process	IDA (16820593)
GO:0048661	positive regulation of smooth muscle cell proliferation	Biological Process	IDA (10393673)
GO:0045840	positive regulation of mitosis	Biological Process	IDA (10770212)
GO:0030195	negative regulation of blood coagulation	Biological Process	TAS (16820593)
GO:0030185	nitric oxide transport	Biological Process	IDA (16820593)
GO:0030072	peptide hormone secretion	Biological Process	IDA (10770212)
GO:0019722	calcium-mediated signaling	Biological Process	IDA (10770212)
GO:0019229	regulation of vasoconstriction	Biological Process	IEA
GO:0014065	phosphoinositide 3-kinase cascade	Biological Process	IDA (17078114)
GO:0007267	cell-cell signaling	Biological Process	IDA (12379507)
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IDA (17078114)
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	Biological Process	IDA (16820593)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000078401

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: