ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

19127

Symbol:

Prop1

Full Name:

paired like homeodomain factor 1

Alias:

Prop-1|df

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1.3|11 25.0 cM

Physical Location:

50764307-50767133 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5626 Symbol (Name): PROP1 (PROP paired-like homeobox 1)

Ortholog Status:

The human GeneID 5626 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw3	Acute Alcohol Withdrawal	11	20	16-28 (cM)	4.1	1.00E-05	Significant	PARC
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008936.1	NP_032962.1	NC_000077.5 range: 50764307..50767133, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005667	transcription factor complex	Cellular Component	IDA (16678101)
GO:0008022	protein C-terminus binding	Molecular Function	IPI (16678101)
GO:0008013	beta-catenin binding	Molecular Function	IPI (16678101)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003682	chromatin binding	Molecular Function	IDA (16678101)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (16678101)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (16678101)
GO:0048732	gland development	Biological Process	IMP (16556738)
GO:0048850	hypophysis morphogenesis	Biological Process	IMP (16678101)
GO:0060070	Wnt receptor signaling pathway through beta-catenin	Biological Process	IGI (16678101)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (16678101)
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (16556738)
GO:0021979	hypothalamus cell differentiation	Biological Process	IMP (9067988)
GO:0009953	dorsal/ventral pattern formation	Biological Process	IMP (12183375\|15459176)
GO:0009887	organ morphogenesis	Biological Process	IMP (12183375\|15459176)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0001568	blood vessel development	Biological Process	IMP (16556738)
GO:0060126	somatotropin secreting cell differentiation	Biological Process	IMP (6194978)