ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

19228

Symbol:

Pthr1

Full Name:

parathyroid hormone receptor 1

Alias:

PPR|PTH1R|Pthr

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F|9 58.0 cM

Physical Location:

110624757-110644803 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5745 Symbol (Name): PTHR1 (parathyroid hormone receptor 1)

Ortholog Status:

The human GeneID 5745 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011199.2	NP_035329.2	NC_000075.5 range: 110624757..110644803, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IDA (8895385)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0004930	G-protein coupled receptor activity	Molecular Function	IEA
GO:0004991	parathyroid hormone receptor activity	Molecular Function	IMP (9832460)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0004991	parathyroid hormone receptor activity	Molecular Function	TAS (11606467)
GO:0008285	negative regulation of cell proliferation	Biological Process	IMP (12194850)
GO:0008284	positive regulation of cell proliferation	Biological Process	IGI (16476422)
GO:0001501	skeletal development	Biological Process	IMP (8662561\|11606467)
GO:0030282	bone mineralization	Biological Process	IMP (9832460\|11606467)
GO:0045453	bone resorption	Biological Process	IMP (9832460)
GO:0007200	G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	Biological Process	IMP (12194850)
GO:0007189	G-protein signaling, adenylate cyclase activating pathway	Biological Process	IMP (9832460)
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	IEA
GO:0006874	cellular calcium ion homeostasis	Biological Process	IMP (9832460)
GO:0002076	osteoblast development	Biological Process	IMP (9832460)
GO:0002062	chondrocyte differentiation	Biological Process	IMP (9832460)
GO:0002062	chondrocyte differentiation	Biological Process	IGI (16476422)
GO:0001503	ossification	Biological Process	IMP (12194850)
GO:0048469	cell maturation	Biological Process	IMP (12194850)