ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ptk2b

Full Name:

PTK2 protein tyrosine kinase 2 beta

Alias:

A6|CADTK|CAKB|CAK[B]|CAKbeta|E430023O05Rik|FAK2|PKB|PTK|PYK2|Raftk

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D1|14 28.0 cM

Physical Location:

66772098-66899888 on NC_000080.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2185 Symbol (Name): PTK2B (PTK2B protein tyrosine kinase 2 beta)

Ortholog Status:

The human GeneID 2185 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_172498.2	NP_766086.1	NC_000080.5 range: 66772098..66899888, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005925	focal adhesion	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (11274221)
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0004715	non-membrane spanning protein tyrosine kinase activity	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IDA (11274221)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IDA (11274221)
GO:0007172	signal complex assembly	Biological Process	IEA