ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ptpn4

Full Name:

protein tyrosine phosphatase, non-receptor type 4

Alias:

PTPMEG|Ptn4|TEP|TEP/mPTPMEG|hPTP-MEG

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 41.5 cM

Physical Location:

121554668-121733647 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5775 Symbol (Name): PTPN4 (protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte))

Ortholog Status:

The human GeneID 5775 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_019933.2	NP_064317.2	NC_000067.5 range: 121554668..121733647, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0019898	extrinsic to membrane	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	RCA (12466851)
GO:0005737	cytoplasm	Cellular Component	RCA (12466851)
GO:0004727	prenylated protein tyrosine phosphatase activity	Molecular Function	RCA (12466851)
GO:0016791	phosphoric monoester hydrolase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008092	cytoskeletal protein binding	Molecular Function	IEA
GO:0004721	phosphoprotein phosphatase activity	Molecular Function	RCA (12466851)
GO:0004725	protein tyrosine phosphatase activity	Molecular Function	IEA
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	Molecular Function	IDA (11054567)
GO:0005515	protein binding	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0005198	structural molecule activity	Molecular Function	RCA (12466851)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0007242	intracellular signaling cascade	Biological Process	RCA (12466851)
GO:0016311	dephosphorylation	Biological Process	IEA
GO:0006470	protein amino acid dephosphorylation	Biological Process	RCA (12466851)