ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ptprn

Full Name:

protein tyrosine phosphatase, receptor type, N

Alias:

IA-2|KIAA4064|mIA-A|mKIAA4064

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C3|1 41.0 cM

Physical Location:

75243615-75260782 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5798 Symbol (Name): PTPRN (protein tyrosine phosphatase, receptor type, N)

Ortholog Status:

The human GeneID 5798 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC
Lore1	Alcohol-induced Loss of Righting Reflex	1		36.9-41 (cM)	5.4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008985.2	NP_033011.2	NC_000067.5 range: 75243615..75260782, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005624	membrane fraction	Cellular Component	TAS (11126414)
GO:0005886	plasma membrane	Cellular Component	TAS (11126414)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0004725	protein tyrosine phosphatase activity	Molecular Function	TAS (11126414)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016791	phosphoric monoester hydrolase activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0006470	protein amino acid dephosphorylation	Biological Process	IEA
GO:0016311	dephosphorylation	Biological Process	IEA
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	Biological Process	TAS (11126414)