ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ren1

Full Name:

renin 1 structural

Alias:

D19352|Ren|Ren-1|Ren-A|Ren1c|Ren1d|Rn-1|Rnr

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 E4|1 69.9 cM

Physical Location:

135247142-135256899 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5972 Symbol (Name): REN (renin)

Ortholog Status:

The human GeneID 5972 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (10318840)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0004195	renin activity	Molecular Function	IEA
GO:0004194	pepsin A activity	Molecular Function	IEA
GO:0004190	aspartic-type endopeptidase activity	Molecular Function	IEA
GO:0042756	drinking behavior	Biological Process	IMP (10617578)
GO:0002003	angiotensin maturation	Biological Process	IMP (10617578)
GO:0009755	hormone-mediated signaling	Biological Process	IDA (14583438)
GO:0008065	establishment of blood-nerve barrier	Biological Process	IMP (10617578)
GO:0006508	proteolysis	Biological Process	IEA
GO:0002016	regulation of blood volume by renin-angiotensin	Biological Process	IMP (10617578)
GO:0048469	cell maturation	Biological Process	IMP (10617578)