ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MARK2

Full Name:

MAP/microtubule affinity-regulating kinase 2

Alias:

EMK1|MGC99619|PAR-1|Par1b

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11q12-q13

Physical Location:

63363470-63433632 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MARK2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001039468.1	NP_001034557.1	NC_000011.8 range: 63363470..63433632
NM_001039469.1	NP_001034558.1	NC_000011.8 range: 63363470..63433632
NM_004954.3	NP_004945.3	NC_000011.8 range: 63363470..63433632
NM_017490.2	NP_059672.2	NC_000011.8 range: 63363470..63433632

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0015630	microtubule cytoskeleton	Cellular Component	NR
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IDA (14976552)
GO:0005515	protein binding	Molecular Function	IPI (14676191\|15324659)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	NAS (8274451)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA (14976552)
GO:0000287	magnesium ion binding	Molecular Function	IDA (14976552)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0030154	cell differentiation	Biological Process	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007243	protein kinase cascade	Biological Process	IDA (14976552)
GO:0006468	protein amino acid phosphorylation	Biological Process	NAS (8274451)
GO:0006468	protein amino acid phosphorylation	Biological Process	IDA (14976552)
GO:0045197	establishment and/or maintenance of epithelial cell polarity	Biological Process	IDA (15324659)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000072518

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: