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Gene Information
Gene ID:201163
Symbol:FLCN
Full Name:folliculin
Alias:BHD|DKFZp547A118|FLCL|FLJ45004|FLJ99377|MGC17998|MGC23445
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17p11.2
Physical Location:17056250-17081220 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S1857  16355942
Region:14355942-18355942
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_144606.5NP_653207.1NC_000017.9 range: 17056250..17081220, complement
NM_144997.5NP_659434.2NC_000017.9 range: 17056250..17081220, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0045786negative regulation of cell cycleBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:201163
HGNC:27310
Ensembl:ENSG00000154803
MIM:607273
HPRD:06278
HuGE Navigator:201163
dbSNP:FLCN
GeneCard:FLCN
AceView:FLCN