ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Scn5a

Full Name:

sodium channel, voltage-gated, type V, alpha

Alias:

Nav1.5|Nav1.5c|SkM1|mH1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F3-F4|9 70.0 cM

Physical Location:

119392528-119488133 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6331 Symbol (Name): SCN5A (sodium channel, voltage-gated, type V, alpha subunit)

Ortholog Status:

The human GeneID 6331 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_021544.3	NP_067519.2	NC_000075.5 range: 119392528..119488133, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0001518	voltage-gated sodium channel complex	Cellular Component	RCA (16141072)
GO:0016021	integral to membrane	Cellular Component	RCA (16141072)
GO:0016020	membrane	Cellular Component	RCA (16141072)
GO:0014704	intercalated disc	Cellular Component	IDA (15746173)
GO:0030315	T-tubule	Cellular Component	IDA (15746173)
GO:0005886	plasma membrane	Cellular Component	IDA (15746173)
GO:0005272	sodium channel activity	Molecular Function	IEA
GO:0005261	cation channel activity	Molecular Function	RCA (16141072)
GO:0005248	voltage-gated sodium channel activity	Molecular Function	RCA (16141072)
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0006811	ion transport	Biological Process	RCA (16141072)
GO:0006812	cation transport	Biological Process	RCA (16141072)
GO:0006814	sodium ion transport	Biological Process	RCA (16141072)
GO:0006810	transport	Biological Process	IEA