ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Sfpi1

Full Name:

SFFV proviral integration 1

Alias:

Dis-1|Dis1|PU.1|Sfpi-1|Spi-1|Tcfpu1|Tfpu.1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E3|2 47.5 cM

Physical Location:

90936953-90955912 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6688 Symbol (Name): SPI1 (spleen focus forming virus (SFFV) proviral integration oncogene spi1)

Ortholog Status:

The human GeneID 6688 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011355.1	NP_035485.1	NC_000068.6 range: 90936953..90955912

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005667	transcription factor complex	Cellular Component	IC (11980719)
GO:0005634	nucleus	Cellular Component	IDA (15361867)
GO:0016563	transcription activator activity	Molecular Function	IDA (15100295)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (15361867)
GO:0005515	protein binding	Molecular Function	IPI (16702405)
GO:0003723	RNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IDA (11980719\|14962908)
GO:0043011	myeloid dendritic cell differentiation	Biological Process	IMP (10648399)
GO:0030851	granulocyte differentiation	Biological Process	IDA (11980719)
GO:0030225	macrophage differentiation	Biological Process	IDA (11980719)
GO:0030098	lymphocyte differentiation	Biological Process	IDA (11980719)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (11980719\|14962908)
GO:0006350	transcription	Biological Process	IEA
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (15100295)